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An increased number of resources are allocated on biomarker discovery, but very few of these biomarkers are clinically adopted. To bridge the gap between Biomarker discovery and clinical use, we aim to generate the Biomarker Toolkit. Biomarker Toolkit will ultimately define the characteristics of successful biomarkers and will therefore begin to shape how biomarker studies are performed. We envision that the development of this novel tool will assist guidance of research trajectory from any stage of development to promote their clinical utilisation.
More info 2023An evidence-based framework that helps innovators of small and large enterprises (SEs and LEs) assess their readiness for successful medical device development and deployment.
More info 2023A multi-dimensional checklist to guide the evaluation of point-of-care tests (POCTs) incorporating validity, utility, usability, cost-effectiveness and patient experience. The motivation for this was to improve the efficiency of evidence generation in POCTs and reduce the lead-time for the adoption of novel POCTs.
More info 2019Empowering Research with Innovative Solutions
Point-of-Care Key Evidence Tool (POCKET); a multi-dimensional checklist to guide the evaluation of point-of-care tests (POCTs) incorporating validity, utility, usability, cost-effectiveness and patient experience. The motivation for this was to improve the efficiency of evidence generation in POCTs and reduce the lead-time for the adoption of novel POCTs.
Access Our ToolsAn increased number of resources are allocated on biomarker discovery, but very few of these biomarkers are clinically adopted. To bridge the gap between Biomarker discovery and clinical use, we aim to generate the Biomarker Toolkit. Biomarker Toolkit will ultimately define the characteristics of successful biomarkers and will therefore begin to shape how biomarker studies are performed. We envision that the development of this novel tool will assist guidance of research trajectory from any stage of development to promote their clinical utilisation.
Access Our ToolsMeet Our Dedicated Team of Experts Collaborating to Achieve Excellence
George Hanna trained in laparoscopic and oesophago-gastric surgery at Ninewells Hospital, Dundee, under Professor Sir Alfred Cuschieri. He joined Imperial College in 2003 as Clinical Senior Lecturer, becoming Professor of Surgical Sciences in 2008. He served as Head of Division of Surgery from 2012 and Head of Department of Surgery and Cancer from 2018. His clinical work at Hammersmith Hospital focuses on oesophageal and gastric cancer and advanced laparoscopic surgery. Additionally, he leads a research program on point-of-care diagnostics and competency assessment tools for surgical training and quality assurance.
Christopher Peters, trained in Leeds, pursued a PhD at Cambridge under Professor Rebecca Fitzgerald, where he developed a four-gene signature for predicting outcomes in oesophageal adenocarcinoma, validated in 371 cases. He initiated the OCCAMS collaboration, leading the International Cancer Genome Consortium's Whole Genome sequencing project. OCCAMS has recruited over 4000 patients and generated numerous publications in prestigious journals. Now a Clinical Senior Lecturer and Consultant Upper GI surgeon at Imperial College London, he focuses on transitioning new technologies to patients. As Biomarker lead for the NIHR London IVD Co-operative, he aims to identify Biomarkers with clinical potential, bridging the gap between discovery and clinical success.
Melody is a Senior Research Fellow and leads the Health Technology Assessment theme within NIHR London IVD Cooperative, which is an NIHR infrastructure for evaluating diagnostics and medical devices. Her work encompasses decision making, statistics, Bayesian networks, behavioural sciences and health technology assessments with the overall aim of improving the quality of decision making in the contexts of surgical quality, patient safety and healthcare innovations. She collaborates widely with researchers, industry, regulators, HTA agencies and policy makers.
Peter, Principal Research Fellow at Imperial College, leads the Methodology theme and serves as Head of Human Factors at the London IVD Co-operative. He's a Fellow and former President of CIEHF, as well as a Fellow of the International Ergonomics Association and the Royal Society of Public Health. Additionally, he's a member of HSE's Workplace Health Expert Committee and Science and Engineering Evidence Assurance Committee. Peter previously led the Robens Centre for Ergonomics at the University of Surrey and served as director of the Robens Centre for Public Health.
Patrick is a Research Fellow and leads the the Dissemination & Implementation Science theme within the CRUK Convergence Science Centre. His research focuses on supporting the development, implementation, and dissemination of cutting-edge diagnostics and health care services to facilitate the early detection & diagnosis of cancer and optimizing cancer control. Most of his work applies social science methods to explore issues related to the implementation and utilization of medical technologies as well as the planning, organization, and structuring of healthcare delivery services.
Shanshan is a Market Analysis and Access Analyst jointly appointed by the NIHR London IVD Co-op (Imperial College London) and Imperial College Health Partners (ICHP). Besides, she is a Patient and Public Involvement lead for London IVD Co-op. She holds an Honorary Research Associate status at Imperial College London. Currently, she has been evaluating and assessing health technologies that bring value to the NHS and patients from innovative companies globally. Shanshan has a PhD in Innovation, Healthcare and Sustainability Management at Scuola Superiore Sant’Anna di Pisa, Italy. She has experience in working with innovative start-ups and as an entrepreneur.
Omar is a healthcare Innovation consultant and Co-founder at Vita Healthcare Solutions. He is an honorary lecturer at Imperial College London and collaborator to the NIHR London IVD Co-op. He has previously held roles such as Innovation Account Lead at Imperial College Health Partners. He holds Executive MBA (Merit) at Imperial College Business School.
Tayana, a Research Fellow in Human Factors – Artificial Intelligence, holds a PhD in clinical medicine research from Imperial College London. She specializes in evaluating and improving healthcare team communication, decision-making, and organizational aspects. With experience at institutions like King’s College London and The State University of New York at Buffalo, she focuses on assessing innovations in healthcare across various conditions. Tayana recently co-developed an algorithm (MeDiC) to streamline cancer treatment planning and has been recognized for her excellence in research approach and innovation. Her expertise lies in mixed methods, implementation science, and team-based quality improvement strategies.
Tianhui is a PhD student at the London IVD Group. She works on evaluation studies of potential Artificial Intelligence (AI) applications in diagnostics. She is interested in generating an evidence-based framework to guide the evaluation and testing of AI applications for diagnosis during their development and implementation stages. Tianhui has a multidisciplinary background with previous academic experiences in accounting, finance, and business analytics at The Hong Kong Polytechnic University and Warwick Business School.
Bernarda Zamora is a Research Fellow in Health Economics, and holds a PhD in Economics from the University Carlos III of Madrid and a Certificate in Quantitative Finance from Fitch Learning. Previously, she has worked as Senior Economist at the Office of Health Economics, international organisations, and academia. She has extensive experiences in working with companies and public organisations to evaluate access to new medical technologies, including exploring value of diagnostic information, and health economic evaluation. She has also experience in Development Economics with applications to health and education in low and middle-income countries.
Massimo, a Human Factors Specialist and Honorary Research Associate at Imperial College London, holds a PhD in Human-Centred Design from Brunel University London. His research focuses on cognitive differences across generations and design implementations for inclusivity in technological devices. Previously, he worked on projects for Cancer Research UK and in catalyst grants exploring assistive technologies for the ageing population. He also contributed to the European Project Light.Touch.Matters, applying Human-Centred Design to health and wellbeing devices. His interests lie in Inclusive Design and human-driven technology development.
Hannah is a Research Associate in Human Factors at Imperial College London. Hannah completed her PhD in sociology at Loughborough University, where she investigated gender diversity in education, providing recommendations on inclusive practices. Her current work applies social science methods to explore the barriers and opportunities for the adoption of medical technologies into healthcare settings. She is also exploring issues of equality, diversity and inclusion in the development and adoption of in-vitro diagnostics and medical technologies. Her areas of interest are health equity, social justice and inclusive design.
Alice Baggaley went to medical school in Oxford, and after completing an Academic Foundation training post in Aberdeen moved to London for surgical training. She has paused her higher surgical training to pursue a PhD within the Biomarker Assessment, Validation, and Translation team at Imperial College London, with Mr Christopher Peters. Alice's research is focused on refining and validating the Biomarker Toolkit, which aims to improve translation and clinical adoption of biomarkers. Aside from her academic career, Alice is the Trainee Representative for higher surgical trainees within South London and enjoys teaching and supervising students.
Katerina-Vanessa Savva is a Research associate in NIHR London In-Vitro Diagnostic Co-operative, specialising in biomarker translational research and cost evaluation of innovations. Due to her role in the group, she has collaborated with academia and industry to promote the clinical utilisation of innovations. Her undergraduate degree was in Biomedical Sciences while her MRes focused on Biomedical Research. She subsequently completed a PhD at Imperial College London. The focus of her PhD was to develop the Biomarker Toolkit, a tool that would mediate the translation of biomarkers from bench to bedside; thus reducing the costs and time associated with excessive biomarker discovery research.
Shay is a Research Associate in Human Factors at Imperial College London’s HealthTech Research Centre In Vitro Diagnostics. He is also a member of the Cancer Research UK Convergence Science Centre. His work primarily employs a mixed-method research approach to investigate aspects relating to the implementation and utilisation of medical and diagnostic technologies. His interests lie in the utilisation and application of digital technologies such as wearables in health, as well as the evaluation of inclusive and human-driven technologies.
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